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The concentration data reveals a bifurcated Chinese strategy in the US market: while 865 sponsors (59% of the total) have cleared only a single product—suggesting opportunistic commodity plays or post-pandemic pivots—a cohort of 41 sponsors with 10+ clearances commands serious attention. Shanghai United Imaging Healthcare Co., Ltd. (60 clearances) and Shenzhen Mindray Bio-Medical Electronics Co., Ltd. (52 clearances) are not arbitrageurs but credible global MedTech firms building systematic portfolios across imaging, monitoring, and critical-care platforms. Promisemed Hangzhou Meditech Co., Ltd. with 31 clearances occupies a middle tier, demonstrating repeatability without yet matching the R&D depth of the top two. The 556 clearances in the trailing twelve months and 34% share of all foreign clearances signal that Chinese sponsors are no longer niche entrants but structural competitors with both capital and regulatory expertise. The recall record—169 incidents over three years with 25 Class I events—is material but not disqualifying when scaled against 3,333 clearances; it reflects quality-system immaturity more than reckless behavior, and the leading firms' recall rates appear lower than the long-tail commodity players.
The product-code distribution exposes a deliberate two-track approach: high-volume commoditization of low-barrier codes and selective encroachment into established US device categories. Chinese dominance in FXX (Mask, Surgical) with 260 clearances versus 85 US and LZA (Polymer Patient Examination Glove) with 180 versus 79 US reflects pandemic-era supply-chain opportunism and cost arbitrage in consumables where IP protection is thin and substantial equivalence is trivial. More strategically significant is the pattern in DXN (System, Measurement, Blood-Pressure, Non-Invasive) with 122 Chinese clearances against only 15 US and FLL (Continuous Measurement Thermometer) with 96 Chinese versus 13 US—these ratios suggest Chinese sponsors are not merely copying mature US products but flooding categories where incumbent US innovation has stalled or where incumbents have ceded the mid-market to focus on premium hospital segments. The GEX (Powered Laser Surgical Instrument) code, with 125 Chinese clearances versus 99 US, sits at the boundary: it indicates Chinese firms are now filing in capital-equipment categories traditionally defended by US and European patent portfolios, likely through design-around engineering or by targeting predicate devices whose patent cliffs have passed. This is legitimate substantial-equivalence process under FDA rules, but the velocity and code concentration point to coordinated IP mapping and a strategy of predicate-hopping that systematically erodes incumbent moats without direct infringement.
Year-over-year 510(k) clearance count for China-headquartered sponsors. The 2021 spike reflects pandemic-driven mask/glove/oximeter clearances. Steady-state since: ~500-600 clearances/year from 340-470 distinct sponsors.
| Year | Clearances | Unique sponsors | Volume |
|---|---|---|---|
| 2020 | 301 | 203 | |
| 2021 | 625 | 470 | |
| 2022 | 613 | 409 | |
| 2023 | 509 | 351 | |
| 2024 | 509 | 344 | |
| 2025 | 535 | 344 | |
| 2026 | 241 | 174 |
Of the 1,472 unique Chinese sponsors over 5 years, 865 cleared exactly ONE product — the commodity/arbitrage tier. Only 41 firms have built portfolios of 10+ products — the global-firm tier.
Where in China the sponsors are headquartered. The dominant clusters reveal which Chinese industrial centers are most aggressive at US market entry.
| City / Province | 5y Clearances | Unique sponsors | Volume |
|---|---|---|---|
| 3333 | 1472 |
Which medical specialties Chinese sponsors are concentrating in. General/Plastic Surgery dominance reflects the volume tier (surgical masks, gloves, lasers, light-based hair removal). Radiology and Cardiovascular reflect the serious-firm tier (Mindray, United Imaging, Edan).
| Specialty | 5y Clearances | Unique sponsors | Last 12mo |
|---|---|---|---|
| General, Plastic Surgery | 823 | 490 | 135 |
| General Hospital | 493 | 288 | 19 |
| Cardiovascular | 338 | 152 | 67 |
| Radiology | 328 | 96 | 58 |
| Physical Medicine | 279 | 156 | 71 |
| Gastroenterology, Urology | 272 | 104 | 55 |
| Dental | 187 | 98 | 33 |
| Obstetrics/Gynecology | 144 | 76 | 45 |
| Neurology | 126 | 79 | 16 |
| Anesthesiology | 66 | 45 | 17 |
| Unknown | 65 | 36 | 11 |
| Clinical Chemistry | 52 | 33 | 5 |
| Code | Device | Class | Specialty | US clearances | US sponsors | CN clearances | CN sponsors | CN last 12mo | CN/US ratio |
|---|---|---|---|---|---|---|---|---|---|
| FXX | Mask, Surgical | II | General, Plastic Surgery | 85 | 70 | 260 | 227 | 3 | 3.06 |
| LZA | Polymer Patient Examination Glove | I | General Hospital | 79 | 37 | 180 | 129 | 1 | 2.28 |
| GEX | Powered Laser Surgical Instrument | II | General, Plastic Surgery | 99 | 54 | 125 | 62 | 43 | 1.26 |
| DXN | System, Measurement, Blood-Pressure, Non-Invasive | II | Cardiovascular | 15 | 12 | 122 | 53 | 24 | 8.13 |
| FLL | Continuous Measurement Thermometer | II | General Hospital | 13 | 11 | 96 | 68 | 3 | 7.38 |
| IYN | System, Imaging, Pulsed Doppler, Ultrasonic | II | Radiology | 144 | 30 | 92 | 24 | 16 | 0.64 |
| NUH | Stimulator, Nerve, Transcutaneous, Over-The-Counter | II | Neurology | 12 | 12 | 68 | 41 | 7 | 5.67 |
| HGX | Pump, Breast, Powered | II | Obstetrics/Gynecology | 20 | 8 | 68 | 25 | 25 | 3.40 |
| OHS | Light Based Over The Counter Wrinkle Reduction | II | General, Plastic Surgery | 21 | 13 | 64 | 41 | 33 | 3.05 |
| DQA | Oximeter | II | Cardiovascular | 22 | 16 | 56 | 37 | 12 | 2.55 |
| IRP | Massager, Powered Inflatable Tube | II | Physical Medicine | 21 | 16 | 48 | 31 | 10 | 2.29 |
| EIH | Powder, Porcelain | II | Dental | 25 | 11 | 44 | 25 | 4 | 1.76 |
| FYA | Gown, Surgical | II | General, Plastic Surgery | 18 | 13 | 44 | 38 | 3 | 2.44 |
| FMI | Needle, Hypodermic, Single Lumen | II | General Hospital | 27 | 17 | 38 | 16 | 3 | 1.41 |
| FMF | Syringe, Piston | II | General Hospital | 47 | 31 | 37 | 22 | 1 | 0.79 |
| GEI | Electrosurgical, Cutting & Coagulation & Accessories | II | General, Plastic Surgery | 180 | 88 | 33 | 24 | 5 | 0.18 |
| FRO | Dressing, Wound, Drug | — | Unknown | 43 | 35 | 33 | 12 | 4 | 0.77 |
| LNH | System, Nuclear Magnetic Resonance Imaging | II | Radiology | 80 | 29 | 31 | 9 | 8 | 0.39 |
| NGX | Stimulator, Muscle, Powered, For Muscle Conditioning | II | Physical Medicine | 10 | 10 | 27 | 19 | 3 | 2.70 |
| GCJ | Laparoscope, General & Plastic Surgery | II | Gastroenterology, Urology | 84 | 42 | 27 | 18 | 8 | 0.32 |
The country distribution of resolvable predicates (predicates we can match against our 5-year warehouse — 42.7% of total CN-source citations resolve):
| Predicate's HQ country | Distinct CN filers citing | Total citations |
|---|---|---|
| CN | 1088 | 1474 |
| US | 227 | 258 |
| KR | 43 | 47 |
| NL | 24 | 28 |
| MY | 25 | 25 |
| DE | 20 | 21 |
| IT | 17 | 17 |
| FR | 15 | 15 |
| CH | 15 | 15 |
| TW | 13 | 13 |
| DK | 10 | 13 |
| JP | 11 | 13 |
| GB | 11 | 11 |
| IL | 11 | 11 |
| CA | 8 | 9 |
Most-cited predicates regardless of HQ. The dominance of Chinese names tells the ecosystem-flywheel story.
Filtered to just US incumbents whose 510(k) clearances appear as cited predicates in Chinese 510(k) submissions. This is the direct evidence of US-to-CN predicate use.
These are the categories where the predicate-citation graph is dense — multiple Chinese sponsors each citing multiple distinct US predicates. The most active "predicate arbitrage" categories.
| Code | Device | CN filers | Distinct US predicates cited | Total citations |
|---|---|---|---|---|
| FXX | Mask, Surgical | 19 | 5 | 19 |
| OHS | Light Based Over The Counter Wrinkle Reduction | 14 | 9 | 15 |
| LZA | Polymer Patient Examination Glove | 12 | 6 | 12 |
| GEX | Powered Laser Surgical Instrument | 10 | 6 | 10 |
| IYN | System, Imaging, Pulsed Doppler, Ultrasonic | 9 | 8 | 12 |
| IRP | Massager, Powered Inflatable Tube | 9 | 5 | 10 |
| LNH | System, Nuclear Magnetic Resonance Imaging | 7 | 8 | 11 |
| OAP | Laser, Comb, Hair | 7 | 7 | 10 |
| CAW | Generator, Oxygen, Portable | 5 | 3 | 6 |
| GCJ | Laparoscope, General & Plastic Surgery | 5 | 4 | 6 |
| LLZ | System, Image Processing, Radiological | 5 | 3 | 5 |
| KPR | System, X-Ray, Stationary | 4 | 4 | 5 |
| NUC | Lubricant, Personal | 4 | 2 | 4 |
| NXC | Aligner, Sequential | 4 | 4 | 4 |
| NFO | Stimulator, Transcutaneous Electrical, Aesthetic Purposes | 3 | 4 | 5 |
| HIH | Hysteroscope (And Accessories) | 3 | 3 | 4 |
| FLL | Continuous Measurement Thermometer | 3 | 2 | 3 |
| GXY | Electrode, Cutaneous | 3 | 3 | 3 |
Source: each citation extracted from the 510(k) Summary PDF on FDA's accessdata.fda.gov (cdrh_docs). Citations represent K-number references in the document — most are actual predicate-device declarations, some are background/comparative references. Manual spot-check recommended for the highest-stakes findings.
Recall enforcement actions against China-located firms over 3 years. 218 total recalls, 32 Class I (most serious), 33 unique firms. This is the safety-quality signal — and partly indicates which firms FDA is actively scrutinizing.
| Firm | Total Recalls | Class I | Most recent |
|---|---|---|---|
| Jiangsu Shenli Medical Production Co., Ltd. | 87 | 0 | 2024-04-05 |
| GE Healthcare (China) Co., Ltd. | 24 | 0 | 2025-01-31 |
| GE Medical Systems China Co., Ltd. | 21 | 18 | 2025-11-14 |
| Shanghai United Imaging Healthcare Co., Ltd. | 19 | 0 | 2023-03-01 |
| Changchun Wancheng Bio-Electron Co., Ltd. | 11 | 0 | 2025-11-22 |
| Chengdu Ai Qin E-commerce Co., Ltd | 7 | 0 | 2020-06-23 |
| Zhejiang Kindly Medical Devices Co., Ltd. | 6 | 0 | 2021-08-24 |
| Flexicare Medical (Dongguan) Ltd. | 6 | 6 | 2025-07-11 |
| Philips Healthcare (Suzhou) Co., Ltd. | 3 | 0 | 2025-12-03 |
| FENG CHUN YUAN MEDICAL EQUIPMENT (SHENZHEN)CO.,LTD | 3 | 0 | 2024-06-26 |
| Haimen Shengbang Laboratory Equipment Co. Ltd. | 3 | 3 | 2022-07-12 |
| Guangdong Haiou Medical Apparatus Co., Ltd | 2 | 0 | 2022-06-10 |
Studies with at least one China location, last 5y.
| NCT | Title | Sponsor | Status | Phase | Started | N | Results |
|---|---|---|---|---|---|---|---|
| NCT07399574 | Diagnostic Accuracy of A Diquat Quantitative Detection Kit and A Portable Mass Spectrometry System for Quantifying Diquat Concentrations in Human Blood Samples | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Not Yet Recruiting | — | 2026-09-01 | 60 | — |
| NCT07627685 | Prospective Study on the Effectiveness and Safety of Bi-polar Pulse-field Tip-catheter Ablation for Atrial Fibrillation in China（POTENTIAL-AF） | Beijing Anzhen Hospital | Not Yet Recruiting | — | 2026-09-01 | 30,000 | — |
| NCT07593833 | Prospective Sample Collection Study for a Blood-Based cfDNA Methylation Assay for Ovarian Cancer Detection | Tongji Hospital | Not Yet Recruiting | — | 2026-07-01 | 1,000 | — |
| NCT07594249 | Shear Wave Elastography of Peripheral Nerves for Early Diagnosis of ICU-acquired Weakness | First Affiliated Hospital of Wannan Medical College | Not Yet Recruiting | — | 2026-07-01 | 98 | — |
| NCT07617298 | EIT Evaluation of the Impact of Inhaled Nitric Oxide on Ventilation/Perfusion Mismatch in ARDS Patients Receiving Noninvasive Respiratory Support | Ming Zhong | Not Yet Recruiting | — | 2026-06-30 | 40 | — |
| NCT07624318 | Trop2 NMR Concordance Study | AstraZeneca | Not Yet Recruiting | — | 2026-06-15 | 3,400 | — |
| NCT07544654 | DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy | Boehringer Ingelheim | Not Yet Recruiting | PHASE3 | 2026-06-15 | 390 | — |
| NCT07604129 | Transcranial Sonography and Machine Learning for Schizophrenia Identification | Taizhou Second People's Hospital | Not Yet Recruiting | — | 2026-06-15 | 200 | — |
| NCT07626229 | Domain-Specific Large Language Model Assistance for Emergency Neurological Diagnosis and Treatment（DEMAND） | Capital Medical University | Not Yet Recruiting | NA | 2026-06-02 | 1,360 | — |
| NCT07613242 | Multimodal Assisted Diagnosis for Pediatric Respiratory Diseases Using Questionnaires, Cough Sounds, and Breath Sounds | Shanghai Children's Medical Center | Not Yet Recruiting | — | 2026-06-01 | 1,400 | — |
| NCT07616440 | Pilot Study on the Clinical Efficacy of Focused Ultrasound-Mediated Targeted Drug Delivery System Combined With Neoadjuvant Therapy for HER2-Positive Breast Cancer | Second Affiliated Hospital, School of Medicine, Zhejiang University | Recruiting | NA | 2026-06-01 | 20 | — |
| NCT07616323 | Screening LUMBAR Syndrome in Infants With Infantile Hemangiomas | West China Hospital | Not Yet Recruiting | — | 2026-06-01 | 70 | — |
| NCT07620769 | Safety and Efficacy Evaluation of the Radiofrequency Therapeutic Device for the Treatment of Atrophic Acne Scars | CLASSYS Inc. | Not Yet Recruiting | NA | 2026-06-01 | 252 | — |
| NCT07620457 | Spectral Precise Image Study for Coronary Artery | Philips Clinical & Medical Affairs Global | Not Yet Recruiting | — | 2026-06-01 | 200 | — |
| NCT07622771 | Neoadjuvant Radiotherapy Combined With NALIRIFOX and Adebrelimab in pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Randomized, Phase II Clinical Trial | Sun Yat-sen University | Not Yet Recruiting | PHASE2 | 2026-06-01 | 84 | — |
| NCT07622576 | A Comparative Study of the Efficacy of AR Based Amblyopia Training Therapy and Occlusion Therapy in Older Children and Adults With Amblyopia | Second Affiliated Hospital, School of Medicine, Zhejiang University | Not Yet Recruiting | NA | 2026-06-01 | 60 | — |
| NCT07600125 | Evaluation of Fecal Multi-target Biomarkers in the Screening of Digestive Tract Cancers | Xijing Hospital | Not Yet Recruiting | — | 2026-06-01 | 5,000 | — |
| NCT07601191 | AutoFUSE or First-Trimester Ultrasound Scan | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Not Yet Recruiting | NA | 2026-06-01 | 1,000 | — |
| NCT07618936 | Programmed Cell Death Ligand 1 PET/CT in Various PD-L1-Related Disease Patients | Tianjin Medical University | Recruiting | — | 2026-06-01 | 500 | — |
| NCT07590336 | 68Ga-NYM207 PET/CT Imaging in Hepatocellular Carcinoma | Peking Union Medical College Hospital | Not Yet Recruiting | PHASE1 / PHASE2 | 2026-06-01 | 100 | — |
| NCT07620626 | Real-World Study of Woven EndoBridge for Intracranial Aneurysm Treatment | Xuanwu Hospital, Beijing | Not Yet Recruiting | — | 2026-06-01 | 1,000 | — |
| NCT07628478 | Effects of Blood Flow Restriction Training on Body Composition and Maximal Strength in Military Personnel | Yang Liu | Recruiting | NA | 2026-06-01 | 36 | — |
| NCT07618793 | Intermittent Hypoxic Training as Neoadjuvant Therapy for Lung Squamous Cell Carcinoma | zhang yi | Not Yet Recruiting | PHASE2 | 2026-06-01 | 60 | — |
| NCT07603700 | STRATEGY-PE: Real-World Treatment Strategies for Intermediate-High Risk Pulmonary Embolism | Nanjing First Hospital, Nanjing Medical University | Not Yet Recruiting | — | 2026-06-01 | 1,300 | — |
| NCT06826469 | The Efficacy and Safety of Task-state-based Temporal Interference Stimulation (TI) in the Treatment of Patients With Depression | First Affiliated Hospital of Zhejiang University | Not Yet Recruiting | NA | 2026-06-01 | 43 | — |
| NCT07620444 | Spectral Precise Image-Colon Cancer | Philips Clinical & Medical Affairs Global | Not Yet Recruiting | — | 2026-06-01 | 100 | — |
| NCT07574502 | Transcutaneous Electrical Acustimulation on Postoperative Bowel Function Recovery in Elderly Patients | Sir Run Run Shaw Hospital | Not Yet Recruiting | NA | 2026-06-01 | 190 | — |
| NCT07613424 | A Study of MET Concordance and Gene Profiling in 1L NSCLC (Genomet) | AstraZeneca | Not Yet Recruiting | NA | 2026-05-31 | 1,000 | — |
| NCT07607236 | Muscle Ultrasound for Sarcopenia Assessment in Kidney Transplant Recipients | Sichuan Provincial People's Hospital | Not Yet Recruiting | — | 2026-05-30 | 140 | — |
| NCT07590284 | Sonazoid CEUS for Early HCC Surveillance | Tianjin Third Central Hospital | Not Yet Recruiting | NA | 2026-05-30 | 556 | — |
| NCT07612501 | Efficacy and Safety of Transcranial Temporal Interference Stimulation for Depression | Yonggui Yuan | Not Yet Recruiting | NA | 2026-05-30 | 60 | — |
| NCT07601997 | Safety and Feasibility of Transcatheter Injectable Hydrogel in Acute STEMI Reperfusion Injury (REFINE Study) | Myomed Technology (Shaoxing) Co., Ltd. | Not Yet Recruiting | NA | 2026-05-30 | 20 | — |
| NCT07596134 | Multimodal Thermal Therapy With Targeted and Immunotherapy for Untreated Unresectable HCC | Zhejiang University | Not Yet Recruiting | NA | 2026-05-25 | 166 | — |
| NCT07625748 | Transcranial Temporal Interference Stimulation for Children With Autism Spectrum Disorders | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | Recruiting | NA | 2026-05-25 | 16 | — |
| NCT07604948 | Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period | Guangzhou Sport University | Recruiting | NA | 2026-05-22 | 34 | — |
| NCT07625540 | Subthalamic Nucleus-Targeted Transcranial Temporal Interference Stimulation for Motor and Non-Motor Symptoms in Parkinson's Disease | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | Recruiting | NA | 2026-05-20 | 32 | — |
| NCT07625007 | Shortwave Intervention for Diabetic Peripheral Neuropathy: A Randomized, Single-Blind, Sham-Controlled Trial(SIDPN) | Chongqing Medical University | Recruiting | NA | 2026-05-20 | 202 | — |
| NCT07483359 | Conversion Therapy With FOLFOX-HAIC Plus Lenvatinib And Tislelizumab For Hepatocellular Carcinoma With Vp3 Portal Vein Tumor Thrombus | First Hospital of China Medical University | Recruiting | PHASE2 | 2026-05-20 | 38 | — |
| NCT07612774 | CAPER-EVO: a Randomized Serial PCCT Trial of Early Evolocumab After ACS | West China Hospital | Recruiting | PHASE4 | 2026-05-19 | 233 | — |
| NCT07524699 | A Study About Remote and Local Liver Surgery | Tongji Hospital | Not Yet Recruiting | NA | 2026-05-16 | 148 | — |
Papers with affiliations in China or major Chinese cities, last 5y.
| PMID | Title | Journal | Authors | Date | Why |
|---|---|---|---|---|---|
| 42207915 · DOI | AI-assisted teams outperform AI-led teams but not human-only teams in assessing research reproducibility in quantitative social science. | Proceedings of the National Academy of Sciences of the United States of America | A Castillo Alvarez G, Abdelhady M, Abdelmoula Y, Aguirre T et al. | 2026-06-02 | Sponsor |
| 42216631 · DOI | SNR-Enhanced Whole-Brain Chemical Exchange Saturation Transfer Imaging by Optimized Variable Flip Angles. | Magnetic resonance in medicine | Dai Z, Hsu YC, Lu S, Su C et al. | 2026-05-30 | Sponsor |
| 41863923 · DOI | Binding characteristics and mechanisms underlying the enhanced stability of anthocyanins by proteins screened with molecular docking. | Food chemistry | He Y, Li B, Li Z, Quintana R et al. | 2026-05-30 | Sponsor |
| 42212698 · DOI | Near-point-of-care diagnosis of tuberculosis with LyocartE MTB Assay: a multicentre diagnostic accuracy study. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | Jing W, Li H, Li L, Ma X et al. | 2026-05-29 | Sponsor+KW |
| 42213369 · DOI | Prognosis and risk stratification in first-presentation myocardial infarction with nonobstructive coronary arteries using stress cardiac MRI. | Insights into imaging | Guo H, Li H, Li K, Long Q et al. | 2026-05-29 | Sponsor |
| 42216194 · DOI | Comparison of linear and angular cephalometric measurements in CBCT using semi-automated software and artificial intelligence-generated cephalograms. | BMC oral health | Aksoy S, Ersalıcı I, Ezhov M, Gusarev M et al. | 2026-05-29 | Sponsor |
| 42213841 · DOI | Contrast-sparing CT using renal-clearable gold nanoclusters for early spatial mapping of renal dysfunction. | Science advances | Caravan P, Catalano OA, Li D, Ma H et al. | 2026-05-29 | Sponsor |
| 42216007 · DOI | Long-term exposure to polystyrene microplastics exacerbates seizure symptoms via lipid metabolic disruption and ferroptosis: insights from multi-omics analyses. | Journal of nanobiotechnology | Deng X, Dou J, Hu S, Liu Y et al. | 2026-05-29 | Sponsor |
| 42215867 · DOI | AARS1 promotes diabetic kidney disease through rewiring Akt and NF-κB signaling to suppress autophagy and sustain inflammation. | Cellular & molecular biology letters | Agborbesong E, Guan C, Li X, Mou S et al. | 2026-05-29 | Sponsor |
| 42214405 · DOI | VRON-0200 alone and in combination with investigational antivirals for participants with chronic hepatitis B virus infection receiving stable nucleos(t)ide therapy: a phase 1b, randomised, open-label, multicentre trial. | The Lancet. Microbe | Bonhomme M, Currie S, Gane E, Lim TH et al. | 2026-05-29 | Sponsor |
| 42213313 · DOI | Tolvaptan for hyponatremia in patients with cirrhosis: a post hoc subgroup analysis of a multicenter, randomized, double-blind, placebo-controlled trial. | Hepatology international | Cai X, Chen C, Chen Y, Cheng J et al. | 2026-05-29 | Sponsor |
| 42216253 · DOI | Flight of the dragons: a global review of migration in Odonata. | Biological reviews of the Cambridge Philosophical Society | Chapman JW, Hayward A, Hedlund JSU, Menz M | 2026-05-29 | Sponsor |
| 42215489 · DOI | An open multi-center MEG-EEG dataset for studying conscious visual perception. | Scientific data | Bonacchi N, Brown T, Das D, Ferrante O et al. | 2026-05-29 | Sponsor |
| 42209879 · DOI | Multiscale feature fusion for few-shot medical image learning with fisher information-driven layer selection. | Visual computing for industry, biomedicine, and art | Chen X, Pang B, Peng Y, Zhang K | 2026-05-29 | Sponsor |
| 42209516 · DOI | Superior dorsal nigral hyperintensity depiction at 7 T MRI using CLEAR-DESS improves diagnosis performance of Parkinson's disease. | NPJ Parkinson's disease | Bai HX, Chen R, He J, Hsu Y et al. | 2026-05-28 | Sponsor |
| 42153573 · DOI | Feedback loops between DNMT1 and autophagy as well as senescence promotes organ aging and canities. | Autophagy | Li L, Li LX, Li X, Liu H et al. | 2026-05-28 | Sponsor |
| 42206348 · DOI | Overcoming the Surface Instability Bottleneck in High-Mobility Crystalline Indium Oxide Thin-Film Transistors by Yttrium Oxide Stabilization. | ACS nano | Fan J, Ge Q, Ju S, Li J et al. | 2026-05-28 | Sponsor |
| 42210008 · DOI | SPP1 in Immunosuppressive Signaling in Lung Adenocarcinoma: Bulk and Single-Cell Transcriptomic Analysis. | Cell biochemistry and biophysics | Jiao L, Li F, Liu Y, Shi JX et al. | 2026-05-28 | Sponsor |
| 42207433 · DOI | Exploration of Real-World Data Sources in Latin America, Middle East and North Africa, and Asia Pacific, to Support Oncology Evidence Generation: A Targeted Literature Review and Regional Recommendations. | Advances in therapy | Bazarbashi S, Chiu A, Dreyer N, Ghai C et al. | 2026-05-28 | Sponsor |
| 42209477 · DOI | Author Correction: A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells. | Nature communications | Barkestani MN, Fan M, Fang C, Geirsson A et al. | 2026-05-28 | Sponsor |
| 42207228 · DOI | A multisociety consensus statement on a new common definition and diagnostic criteria for PSVD or NCPF. | Hepatology international | Alves VAF, Aqul A, Cerda E, Darwish Murad S et al. | 2026-05-28 | Sponsor |
| 42207983 · DOI | Staffing, Accepted Indications and Dose of Phase II Cardiac Rehabilitation: Country Income Class and Time-Based Comparisons from the International Council of Cardiovascular Prevention and Rehabilitation's (ICCPR) 2025 Audit Update. | European journal of preventive cardiology | Anchique CV, Batalik L, Botha NVH, Champaiboon J et al. | 2026-05-28 | Sponsor |
| 42097137 · DOI | Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome. | Cell | Abbasi F, Assimes TL, Björck HM, Björkander S et al. | 2026-05-28 | Sponsor |
| 42213858 · DOI | Comparison of the EORTC QLQ-EN24, FACT-En, and FEnSI-23 for assessing quality of life in endometrial cancer: a systematic review. | Current opinion in supportive and palliative care | Bottomley A, Cella D, Chan AW, Chow E et al. | 2026-05-28 | Sponsor |
| 42209725 · DOI | Transcription-independent induction of rapid-onset senescence is integral to healing. | Nature cell biology | Cherfils-Vicini J, Dahlhoff M, Dworak H, Efraimoglou C et al. | 2026-05-28 | Sponsor |
| 42207056 · DOI | Impact of atopic dermatitis on education and career choices: the Scars of Life international study. | The Journal of investigative dermatology | Aslanian FP, Begolka WS, Burstein S, Demessant-Flavigny AL et al. | 2026-05-28 | Sponsor |
| 42213789 · DOI | Action and rest tremor map to distinct networks within the primary motor cortex. | Cell reports | Al-Fatly B, Fox MD, Goede LL, Horn A et al. | 2026-05-28 | Sponsor |
| 42210642 · DOI | Rapid Generation of Subject-Specific Human Models With Detailed Tissue Structures for Timely Individualized SAR Assessment. | Magnetic resonance in medicine | He J, Hu J, Huang Y, Li Z et al. | 2026-05-28 | Sponsor |
| 42204304 · DOI | Robust multicentre detection and classification of colorectal liver metastases on CT: application of foundation models. | NPJ precision oncology | Aichert A, Bobowicz M, Faggioni L, Francischello R et al. | 2026-05-27 | Sponsor |
| 42202721 · DOI | Withdrawal notice to "Relationship between coronary microvascular dysfunction (CMD) and left ventricular diastolic function in patients with symptoms of myocardial ischemia with non-obstructive coronary artery disease (INOCA) by cardiovascular magnetic resonance feature-tracking"[ClinRad 79(7) (July 2024) 536-543. | Clinical radiology | An J, Cao J, He Y, Kong H et al. | 2026-05-27 | Sponsor |
Pre-prints whose corresponding-author institution mentions China or major Chinese cities. Leading-edge signal.
| DOI / Platform | Title | Corresponding author + institution | Category | Posted | Peer-reviewed? |
|---|---|---|---|---|---|
|
biorxiv v7
10.1101/2025.06.27.661923
|
Functional coherence of bacterial ecospecies |
Sarah Lauren Svensson
Shanghai Institute of Immunity and Infection / Chinese Academy of Sciences
|
microbiology | 2026-06-05 | Published |
|
medrxiv
10.64898/2026.06.04.26354880
|
Education/training for health workers/students on inclusive and gender-affirmative care for trans and gender-diverse people: a systematic review |
Jun Xia
Nottingham Ningbo GRADE Centre, School of Economics, University of Nottingham Ningbo, China
|
health policy | 2026-06-05 | Published |
|
biorxiv
10.64898/2026.06.04.730176
|
Microfluidic-based high-throughput isolation enhances the recovery of novel strains and diversity from Arctic soil microbiome |
Li Liao
Polar Research Institute of China
|
microbiology | 2026-06-04 | Published |
|
medrxiv
10.64898/2026.06.02.26354777
|
AIM-PrEP: AI-Agent Driven Multicenter Intervention to Improve PrEP Adherence and Health Monitoring Among Men Who Have Sex with Men (MSM)-Protocol of A Randomized Controlled Trial |
Junjie Xu
Clinical Research Academy, Peking University Shenzhen Hospital, Peking University, Shenzhen, China
|
hiv aids | 2026-06-04 | Published |
|
medrxiv
10.64898/2026.06.02.26354716
|
The Surgical Assessment and Healthcare (SAH) Index: A Risk-Adjusted Framework for Surgeon-Level Quality Audit in Gastric Cancer |
Birendra Kumar Sah
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
|
health systems and quality improvement | 2026-06-03 | Published |
|
biorxiv
10.64898/2026.06.03.729796
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Discovery of ARQ-501 as a potent PafA inhibitor that elevates KatG levels to potentiate isoniazid in mycobacteria |
Qingxiang Sun
UESTC: University of Electronic Science and Technology of China
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microbiology | 2026-06-03 | Published |
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medrxiv
10.64898/2026.05.30.26353749
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A Radiologic Masquerade: Camrelizumab-Associated Breast Lesions That Mimic Progression |
Xiaoling Zhang
Sun Yat-sen University First Affiliated Hospital Department of Radiology Guangzhou, Guangdong, CN
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radiology and imaging | 2026-06-03 | Published |
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medrxiv
10.64898/2026.06.02.26354684
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Oxygen extraction fraction brain charts for human lifespan and application for brain disorders |
Yaou Liu
Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical R…
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neurology | 2026-06-03 | Published |
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biorxiv
10.64898/2026.05.29.728625
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Magnetically guided macrophage immunobots coordinate iron-metabolic cascades and immunogenic ferroptosis for tumor immunotherapy |
Immihan Ceren Yasa
Thrust of Robotics and Autonomous Systems & Thrust of Bioscience and Biomedical Engineering, The Hong Kong University of…
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bioengineering | 2026-06-02 | Published |
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medrxiv
10.64898/2026.06.01.26354560
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Association between maternal history of psychiatric disorders and the risk of cardiovascular disease in offspring up to early middle-age |
Tai Ren
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
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cardiovascular medicine | 2026-06-02 | Published |
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biorxiv
10.64898/2026.05.27.728164
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Engineering xylose metabolism for diverse polyhydroxyalkanoates synthesis in Halomonas TD |
Jian-Wen Ye
South China University of Technology
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bioengineering | 2026-06-01 | Published |
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medrxiv v2
10.64898/2025.12.17.25342447
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Levels and trends in fertility rates among adolescents aged 15-19 in 21 States and Union Territories in India from 1990 to 2050: A Bayesian Modelling Study |
Fengqing Chao
The Chinese University of Hong Kong, Shenzhen
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public and global health | 2026-06-01 | Published |
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biorxiv
10.64898/2026.05.28.728359
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The free-living wellspring of symbiotic nitrogen fixation in Bradyrhizobium |
Haiwei Luo
The Chinese University of Hong Kong
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microbiology | 2026-05-29 | Published |
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biorxiv
10.64898/2026.05.27.728070
|
An SE(3)-equivariant Crystal Structure Prediction Framework for Prospective Identification and Development of Bioactive Nucleoside Self-Assembling Materials |
Han Wang
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, Chi…
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bioengineering | 2026-05-29 | Published |
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medrxiv v4
10.1101/2025.04.13.25325764
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Safety and Efficacy of Vesemnogene Lantuparvovec, an AAV-Based Gene Therapy in Young Children Under 24 Months with Spinal Muscular Atrophy in Low- and-Middle- Income Countries. Second Interim Report (August 2025). |
Austin T. Gao
Lantu Biopharma, Guangzhou, Guangdong Province, China
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genetic and genomic medicine | 2026-05-28 | Published |
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biorxiv
10.64898/2026.05.22.725279
|
A biointegrated living brain stimulator evokes specific neural signalling |
Xuemin Du
Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS)
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bioengineering | 2026-05-27 | Published |
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biorxiv
10.64898/2026.05.23.727373
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An AI-agent-orchestrated grey-box Transformer framework for sparse pharmacokinetic curve reconstruction and pharmacometric model initialization |
Dongyang Liu
Drug Clinical Trial Center, Peking University Third Hospital, Beijing 100191, China; Institute of Medical Innovation, Pe…
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pharmacology and toxicology | 2026-05-27 | Published |
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biorxiv
10.64898/2026.05.24.727447
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BMSC-Laden PEGDA/HAMA Dual-Crosslinked Hydrogels with Distinct Stiffness Profiles for Osteochondral Defect Repair |
Xintao Zhang
Peking University Shenzhen Hospital
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bioengineering | 2026-05-27 | Published |
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medrxiv
10.64898/2026.05.26.26354082
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Disposable versus reusable gastroscope in observation and endoscopic mucosal resection performance: a non-inferiority trial. |
Xianhuan Yan
Daichuan Medical (Shenzhen) Co., Ltd.
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gastroenterology | 2026-05-27 | Published |
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medrxiv v2
10.1101/2025.08.01.25332496
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Association of COVID-19 with risks of all-cause and cause-specific mortality post-infection: A UK Biobank cohort study |
Hon-Cheong SO
The Chinese University of Hong Kong
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infectious diseases | 2026-05-27 | Published |
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medrxiv
10.64898/2026.05.23.26353939
|
Frontier Large Language Models for Comprehensive Medication Review in CKD Patients with Polypharmacy: A Trap-Embedded Synthetic Benchmark |
Hsuan-Ming Lin
An Nan Hospital, China Medical University, Tainan, Taiwan
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health informatics | 2026-05-26 | Published |
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medrxiv
10.64898/2026.05.23.26353923
|
Comparative Study on Image Quality of Deep Learning and Adaptive Statistical Iterative Reconstruction-V in Thin Layer CT of liver Lesions |
Jing Zhang
The second People's Hospital of Changzhou,The Third Affiliated hospital of Nanjing Medical University
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radiology and imaging | 2026-05-26 | Published |
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biorxiv
10.64898/2026.05.20.726718
|
A Time-Sequenced Three-Drug-Loaded Microneedle Patch for the Prevention of Vein Graft Restenosis After Coronary Artery Bypass Grafting |
Bolin Wang
Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University
|
bioengineering | 2026-05-25 | Published |
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medrxiv
10.64898/2026.05.17.26353417
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Identification of amino acid metabolism-related biomarkers in liver fibrosis: a transcriptomic analysis with experimental validation |
Zetong Liu
Northeastern University (China)
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gastroenterology | 2026-05-24 | Published |
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medrxiv v9
10.1101/2025.10.21.25338475
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Digital Registrar: A Schema-First Framework for Multi-Cancer Privacy-Preserving Pathology Abstraction via Local LLMs |
Kai-Po Chang
School of Medicine, China Medical University, Taichung, Taiwan
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health informatics | 2026-05-23 | Published |